Food allergy and anaphylaxis – 2055: Slow specific oral tolerance induction in children with hen’s egg allergy. 3-days on / 4 days off schedule

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Food allergy and anaphylaxis – 2055: Slow specific oral tolerance induction in children with hen’s egg allergy. 3-days on / 4 days off schedule

Methods Seven children aged 9 months to 6.6 years (median 1.7 years) with hen’s egg allergy were performed open oral food challenge tests with boiled hen’s egg to define the threshold dose. Subjects underwent SOTI in which they intake boiled hen’s egg at home 3 days every week. The dose was increased every 1 to 2 weeks from approximately one fourth of the threshold dose to 60g. Clinical respons...

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Specific oral tolerance induction in food allergy.

Specific oral tolerance in food allergy can be induced by oral administration of the offending food, starting with very low dosages, gradually increasing the daily dosage up to an amount equivalent to a usually relevant dose for daily intake, followed up by a daily maintenance dose. Unfortunately, the body of scientific evidence concerning specific oral tolerance induction (SOTI) is still rathe...

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Specific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction.

BACKGROUND Specific oral tolerance induction (SOTI) seems to be a promising treatment of food allergy. Specific oral tolerance induction and elimination diet were compared with respect to efficacy rate and patterns of clinical reaction. METHODS Children with challenge proven immunoglobulin E (IgE)-mediated cow's milk (CM) allergy or hen's egg (HE) allergy were randomly assigned to SOTI or eli...

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Specific Oral Tolerance Induction in Food Allergy in Children: Efficacy and Clinical Patterns of Reaction

who underwent OFCs at the Duke University pediatric allergy-immunology clinic, excluding patients with a history of severe symptoms with previous reactions, were studied. Patient-selection criteria were based on the clinical history, results of skin-prick tests, and foodspecific immunoglobulin E (IgE) levels that were much lower than those previously published levels predictive of a high likeli...

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Food-induced anaphylaxis and oral allergy syndrome.

Case Report A 16-year-old boy presents to the allergy clinic with complaints of perioral itching and tingling after handling apples at his father’s fruit stall. He had experienced such symptoms on previous occasions, but this time he has developed mild lip swelling and tongue itching, as well. He has a history of seasonal allergic rhinitis that is controlled by nasal steroid spray. His father i...

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ژورنال

عنوان ژورنال: World Allergy Organization Journal

سال: 2013

ISSN: 1939-4551

DOI: 10.1186/1939-4551-6-s1-p138